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May 9, 2024

A Breakthrough in Longevity: Uncovering a Key Molecular Pathway for Aging Control


In a fascinating study at the State University of Campinas (UNICAMP) in Brazil, researchers have uncovered significant insights into the aging process through the lens of RNA communication among tissues. This study, published in the journal Gene, explores the dynamics of RNA molecules and their profound impact on lifespan, particularly through the phenomena they have termed Intercellular/Extracellular Systemic RNA imbalance (InExS).

The Role of RNA in Intertissue Communication

The UNICAMP researchers, led by Professor Marcelo Mori, have built on the foundational knowledge of RNA interference, a discovery that won Andrew Fire and Craig Mello the Nobel Prize in Physiology and Medicine in 2006. Their research further illuminates how RNA molecules, traditionally understood merely as messengers of genetic information, are also vital for intercellular communication, influencing the longevity of organisms.

Impacts of RNA Dysregulation on...

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